Apoptosis inducer 24

CAT: 0931-T200071-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T200071-01Size:10 mg
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CAS Number
2763063-09-6
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
Apoptosisinducer 24 (Compound 4) inhibits the proliferation of gastric cancer cells with an IC50 range of 1.2-4.8 ?M. It arrests the cell cycle at the G2/M phase, induces apoptosis in BGC-823 cells, and causes mitochondrial dysfunction. In mice, Apoptosisinducer 24 exhibits antitumor activity without significant toxicity, having an LD50 of 91.2 mg/kg.
Smiles
C(OCCCCOC(=O)C1=CC=C(OCC2=CC=C(C=C2)B3OC(C)(C)C(C)(C)O3)C=C1)(=O)[C@]45[C@]([C@@]6([C@@](C)(CC4)[C@@]7(C)C(=CC6=O)[C@]8(C)[C@@](CC7)(C(C)(C)C(=O)C(C#N)=C8)[H])[H])(CC(C)(C)CC5)[H]
Molecular Formula
C55H70BNO9
Molecular Weight
899.96
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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