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Mouse Pdk4 Antibody

CAT: 0223-58-028Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-028Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Pdk4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism (By similarity) .
NCBI Gene ID
27273
Swiss Prot
O70571
Accession Number
O70571
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Pdk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the N-terminal region of mouse Pdk4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Pdk4
NCBI Official Name
[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 4, mitochondrial
NCBI Organism
Mus musculus
Background Reference 01
Hyvarinen, J., et al. J. Biol. Chem. 285 (18) :13646-13657 (2010)
Background Reference 02
Hwang, B., et al. Biochem. J. 423 (2) :243-252 (2009)
Background Reference 03
Hsieh, M.C., et al. J. Biol. Chem. 283 (41) :27410-27417 (2008)
Background Reference 04
Lai, L., et al. Genes Dev. 22 (14) :1948-1961 (2008)
Other Product Names
[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4, Pdk4
Tested Applications
WB
Physical Properties
Liquid

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