PDK2 Antibody

• Background :

  This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• NCBI Gene ID :

  5164

• Swiss Prot :

  Q15119

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 128-407 of human PDK2 (NP_002602.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  A-549

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 46kDa

• Fragment :

  IgG

• Symbol :

  PDK2

• Positive Control 2 :

  BT-474

• Positive Control 3 :

  HepG2

• Positive Control 4 :

  293T

• NCBI Official Name :

  Pyruvate dehydrogenase kinase, isozyme 2

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PDK2, PDHK2, PDKII

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid