Mouse Pdk2 Antibody

• Background :

  Pdk2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

• NCBI Gene ID :

  18604

• Swiss Prot :

  Q9JK42

• Accession Number :

  Q9JK42

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This Mouse Pdk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-107 amino acids from the N-terminal region of mouse Pdk2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  46 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  Pdk2

• NCBI Official Name :

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 2, mitochondrial

• NCBI Organism :

  Mus musculus

• Background Reference 01 :

  Sun, W., et al. Clin. Cancer Res. 15 (2) :476-484 (2009)

• Background Reference 02 :

  Pagliarini, D.J., et al. Cell 134 (1) :112-123 (2008)

• Background Reference 03 :

  Osafune, K., et al. Development 133 (1) :151-161 (2006)

• Background Reference 04 :

  Papin, J., et al. Curr. Opin. Biotechnol. 15 (1) :78-81 (2004)

• Other Product Names :

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 2, mitochondrial, Pyruvate dehydrogenase kinase isoform 2, PDH kinase 2, Pdk2

• Tested Applications :

  WB, IHC-P

• Physical Properties :

  Liquid