PDK4 Antibody

• Background:

  This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

• NCBI Gene ID:

  5166

• Swiss Prot:

  Q16654

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 102-411 of human PDK4 (NP_002603.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 46kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PDK4

• Positive Control 2:

  HT-1080

• Positive Control 3:

  Mouse uterus

• Positive Control 4:

  Mouse heart

• Positive Control 5:

  Mouse skeletal muscle

• Positive Control 6:

  Rat skeletal muscle

• NCBI Official Name:

  Pyruvate dehydrogenase kinase, isozyme 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PDK4, FLJ40832, PDHK4

• Tested Applications:

  WB

• Physical Properties:

  Liquid