Mouse Pdk3 Antibody

• Background:

  Pdk3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism (By similarity) .

• NCBI Gene ID:

  236900

• Swiss Prot:

  Q922H2

• Accession Number:

  Q922H2

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Pdk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-414 amino acids from the C-terminal region of mouse Pdk3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  Pdk3

• NCBI Official Name:

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 3, mitochondrial

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Pagliarini, D.J., et al. Cell 134 (1) :112-123 (2008)

• Background Reference 02:

  Blackshaw, S., et al. PLoS Biol. (9), E247 (2004) :

• Background Reference 03:

  Visel, A., et al. Nucleic Acids Res. 32 (DATABASE ISSUE), D552-D556 (2004) :

• Background Reference 04:

  Mootha, V.K., et al. Cell 115 (5) :629-640 (2003)

• Other Product Names:

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 3, mitochondrial, Pyruvate dehydrogenase kinase isoform 3, Pdk3

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid