PDK3 Antibody

• Background:

  PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

• NCBI Gene ID:

  5165

• Swiss Prot:

  Q15120

• Accession Number:

  Q15120

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PDK3 antibody is generated from rabbits immunized with human PDK3 recombinant protein.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  47 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PDK3

• NCBI Official Name:

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 3, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Baker, J.C., et al., J. Biol. Chem. 275 (21) :15773-15781 (2000) .

• Background Reference 02:

  Gudi, R., et al., J. Biol. Chem. 270 (48) :28989-28994 (1995) .

• Other Product Names:

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 3, mitochondrial, Pyruvate dehydrogenase kinase isoform 3, PDK3, PDHK3

• Tested Applications:

  WB, Flow

• Protein ID:

  3183119

• Physical Properties:

  Liquid