PDK2 Antibody

• Background:

  PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

• NCBI Gene ID:

  5164

• Swiss Prot:

  Q15119

• Accession Number:

  Q15119

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PDK2 antibody is generated from rabbits immunized with recombinant protein of human PDK2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  46 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PDK2

• NCBI Official Name:

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 2, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Li, J., et al. J. Biol. Chem. 284 (49) :34458-34467 (2009) Fencl, F., et al. Pediatr. Nephrol. 24 (5) :983-989 (2009) Sun, W., et al. Clin. Cancer Res. 15 (2) :476-484 (2009) Hiromasa, Y., et al. Biochemistry 47 (8) :2312-2324 (2008)

• Other Product Names:

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 2, mitochondrial, Pyruvate dehydrogenase kinase isoform 2, PDH kinase 2, PDKII, PDK2, PDHK2

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  21431820

• Physical Properties:

  Liquid