PDK2 Antibody

• Background :

  PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

• NCBI Gene ID :

  5164

• Swiss Prot :

  Q15119

• Accession Number :

  Q15119

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PDK2 antibody is generated from rabbits immunized with recombinant protein of human PDK2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  46 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  PDK2

• NCBI Official Name :

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 2, mitochondrial

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Li, J., et al. J. Biol. Chem. 284 (49) :34458-34467 (2009) Fencl, F., et al. Pediatr. Nephrol. 24 (5) :983-989 (2009) Sun, W., et al. Clin. Cancer Res. 15 (2) :476-484 (2009) Hiromasa, Y., et al. Biochemistry 47 (8) :2312-2324 (2008)

• Other Product Names :

  [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 2, mitochondrial, Pyruvate dehydrogenase kinase isoform 2, PDH kinase 2, PDKII, PDK2, PDHK2

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  21431820

• Physical Properties :

  Liquid