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AFP-07 (free acid)

CAT: 0804-HY-129293Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129293Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AFP-07 free acid is a derivative of 7, 7-difluoroprostacyclic and is a highly potent and selective prostacyclin receptor IP receptor agonist with a Ki value of 0.561 nM[1].
CAS Number
788799-13-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/afp-07-free-acid.html
Solubility
10 mM in DMSO
Smiles
CCC#CC[C@H](C)[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])O/C(C2(F)F)=C\CCCC(O)=O
Molecular Formula
C22H30F2O5
Molecular Weight
412.47
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Chang CS, et al. 7,7-Difluoroprostacyclin derivative, AFP-07, a highly selective and potent agonist for the prostacyclin receptor. Prostaglandins. 1997 Feb;53 (2) :83-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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