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P53 DUBTAC modulator-1

CAT: 0013-GTR19275024-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275024-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P53 DUBTAC modulator-1 (Compound A1) is a modulator of the p53 Y220C DUBTAC (Kd = 12.09 μM) . It effectively reactivates mutant p53 Y220C and promotes its deubiquitination. This compound upregulates p53 Y220C protein levels, induces apoptosis, reduces Bcl-2 levels, and inhibits the Wnt signaling pathway. Additionally, p53 DUBTAC modulator-1 exhibits anticancer activity against liver cancer.
Storage Conditions
-20°C
Notes
For research use only.

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