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Apoptosis inducer 45

CAT: 0013-GTR19273067-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273067-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Apoptosis inducer45 is an apoptosis inducer demonstrating cytotoxic activity against the MCF-7 cell line. It initiates apoptosis in these cells via the mitochondrial pathway by increasing the Bax/Bcl-2 ratio, leading to the cleavage of caspase-9 and subsequent fragmentation of the DNA repair protein PARP. Additionally, Apoptosis inducer45 induces the cleavage of caspase-8, which subsequently triggers the cleavage of caspase-3 and its downstream target PARP, resulting in extrinsic apoptosis. This compound is applicable in breast cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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