Ac-Exatecan-d5

• UNSPSC Description:

  Ac-Exatecan-d5 is the deuterium labeled Ac-Exatecan (HY-79490)[1].

• Target Antigen:

  ADC Cytotoxin; Isotope-Labeled Compounds; Topoisomerase

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Others

• Field of Research:

  Others

• Purity:

  99.93

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1OCC(C(N2C(C3=NC4=CC(F)=C(C5=C4C([C@H](CC5)NC(C)=O)=C3C2)C)=C6)=O)=C6[C@]1(C([2H])(C([2H])([2H])[2H])[2H])O

• Molecular Weight:

  482.52

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported