Ac-Exatecan-d5

• Description :

  Ac-Exatecan-d5 is the deuterium labeled Ac-Exatecan (HY-79490) [1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Payload; Isotope-Labeled Compounds; Topoisomerase

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Others

• Field of Research :

  Others

• Purity :

  99.93

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1OCC(C(N2C(C3=NC4=CC(F)=C(C5=C4C([C@H](CC5)NC(C)=O)=C3C2)C)=C6)=O)=C6[C@]1(C([2H])(C([2H])([2H])[2H])[2H])O

• Molecular Formula :

  C26H19D5FN3O5

• Molecular Weight :

  482.52

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-220.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported