Exatecan Intermediate 1-d5

• Description:

  Exatecan Intermediate 1-d5 is the deuterium labeled Exatecan Intermediate 1[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Payload; Isotope-Labeled Compounds; Topoisomerase

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Others

• Field of Research:

  Others

• Purity:

  99.90

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N2C (C (CC2) =O) =CC ([C@@] (C ([2H]) (C ([2H]) ([2H]) [2H]) [2H]) 3O) =C1COC3=O

• Molecular Formula:

  C13H8D5NO5

• Molecular Weight:

  268.28

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  1346617-23-9