Exatecan Intermediate 1-d5

• Description :

  Exatecan Intermediate 1-d5 is the deuterium labeled Exatecan Intermediate 1[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Payload; Isotope-Labeled Compounds; Topoisomerase

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Others

• Field of Research :

  Others

• Purity :

  99.90

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N2C(C(CC2)=O)=CC([C@@](C([2H])(C([2H])([2H])[2H])[2H])3O)=C1COC3=O

• Molecular Formula :

  C13H8D5NO5

• Molecular Weight :

  268.28

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1346617-23-9]