Ac-Exatecan

• Target:

  ADC Cytotoxin|||Topoisomerase

• Related Pathways:

  Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Purity:

  0.9709

• Bioactivity:

  Ac-Exatecan (Ac-DX-8951) is acetylation-modified Exatecan.Exatecan (DX-8951) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 ?M and antitumor activity.

• Smiles:

  N(C(C)=O)[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6

• Molecular Formula:

  C26H24FN3O5

• Molecular Weight:

  477.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2922852-48-8