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Ac-Exatecan

CAT: 0931-T77901-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T77901-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2922852-48-8
Target
ADC Cytotoxin, Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Purity
0.9709
Bioactivity
Ac-Exatecan (Ac-DX-8951) is acetylation-modified Exatecan.Exatecan (DX-8951) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM and antitumor activity.
Smiles
N(C(C)=O)[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
Molecular Formula
C26H24FN3O5
Molecular Weight
477.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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