Ac-Exatecan

• Target :

  ADC Cytotoxin|||Topoisomerase

• Related Pathways :

  Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Purity :

  0.9709

• Bioactivity :

  Ac-Exatecan (Ac-DX-8951) is acetylation-modified Exatecan.Exatecan (DX-8951) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 ?M and antitumor activity.

• Smiles :

  N(C(C)=O)[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6

• Molecular Formula :

  C26H24FN3O5

• Molecular Weight :

  477.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2922852-48-8