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PROTAC SMARCA2 degrader-7

CAT: 0013-GTR19238082-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238082-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACSMARCA2 degrader-7 (I-428) is a heterobifunctional molecule that induces targeted degradation of the SWI/SNF catalytic subunits SMARCA2 and SMARCA4, with DC50 values below 100 nM and 100-500 nM in MV411 cells, respectively. This tool compound is used in vitro to probe SWI/SNF complex function in oncology and epigenetics research.
CAS Number
2568277-71-2
Field of Research
Neuroscience
Smiles
C (C12CCC (C (N[C@H] (C (=O) N3[C@H] (C (NCC4=CC=C (C=C4) C5=C (C) N=CS5) =O) C[C@@H] (O) C3) C (C) (C) C) =O) (CC1) CC2) N6CCC (CC6) N7C=C (C=N7) C=8C=C (N=NC8N) C9=C (O) C=CC=C9
Molecular Formula
C50H62N10O5S
Molecular Weight
915.16
Storage Conditions
-20°C
Notes
For research use only.

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