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PROTAC SMARCA2 degrader-8

CAT: 0013-GTR19238018-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238018-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACSMARCA2 degrader-8 (compound 1) is a potent and selective small molecule degrader of the SMARCA2 (BRM) protein. It demonstrates high cellular potency with a DC50 of 28 nM in A375 melanoma cells, making it a valuable chemical probe for investigating SWI/SNF chromatin remodeling complex function in cancer biology and targeted protein degradation research.
CAS Number
2669027-50-1
Field of Research
Neuroscience
Smiles
C ([C@@H] (NC (=O) C=1C=C (N=CC1) N2CCN (CC2) C=3C=C (N=NC3N) C4=C (O) C=CC=C4) C (C) (C) C) (=O) N5[C@H] (C (N[C@@H] (C) C6=CC=C (C=C6) C7=C (C) N=CS7) =O) C[C@@H] (O) C5
Molecular Formula
C43H50N10O5S
Molecular Weight
818.99
Storage Conditions
-20°C
Notes
For research use only.

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