KT-333 ammonium

CAT: 0013-GTR19235059-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19235059-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

KT-333 ammonium is a molecular glue degrader that selectively targets STAT3 for ubiquitin-proteasome degradation by recruiting the VHL E3 ligase. It demonstrates potent antitumor activity in research models of hematologic malignancies such as T-cell lymphomas and leukemias, supporting its use in both in vitro and in vivo oncology studies.

CAS Number

2839758-34-6

Field of Research

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Smiles

ClC (C (CCCC (N[C@@H] (C (C) (C) C) C (N1[C@@H] (C[C@H] (C1) O) C (N[C@H] (C2=CC=C (C3=C (N=CS3) C) C=C2) C) =O) =O) =O) =CC=C4) =C4OC[C@H] (CCC (N) =O) NC ([C@H]5N6[C@] (CCN (C[C@@H] (C6=O) NC (C7=CC8=CC (C (P (O) ([O-]) =O) =O) =CC=C8N7) =O) C (C) =O) ([H]) CC5) =O.[NH4+]

Molecular Formula

C60H77ClN11O14PS

Molecular Weight

1274.81

Storage Conditions

-20°C

Notes

For research use only.

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T86788-01	KT-333 ammonium
HY-156730A	KT-333 (ammonium)
HY-156730-01	KT-333
HY-156730B	KT-333 (diammonium)
T88365-01	KT-333 diammonium
B6673-.025	KT 5823
6738/10	KT 182
T200088-01	KT D606
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MBS515006-01	KT-5823

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