Products for Research Use Only
RegisterLogin

KT D606

CAT: 0013-GTR19239274-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19239274-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KT D606 is a small molecule PAK kinase inhibitor (IC50 = 4 μM) that selectively targets oncogenic RAS-driven cancer cell proliferation. It serves as a valuable research tool for investigating the RAS/PAK1 signaling axis in both cellular and animal models of cancer.
CAS Number
1429063-06-8
Field of Research
Signal Transduction
Smiles
C[C@]12N3C=4C5=C (C6=C (C4C=7C3=CC=CC7) C (CCCCCCCC8C=9C%10=C%11C%12=C (C9C (=O) N8) C=%13C (N%12[C@@]%14 (O[C@] (C) (N%11C=%15C%10=CC=CC%15) [C@] (C (O) =O) (O) C%14) [H]) =CC=CC%13) NC6=O) C=%16C (N5[C@] (O1) (C[C@@]2 (C (O) =O) O) [H]) =CC=CC%16
Molecular Formula
C59H50N6O10
Molecular Weight
1003.06
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(15S,16R,18R)-5-[7-[(15R,17R,18S)-17-carboxy-17-hydroxy-18-methyl-5-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaen-3-yl]heptyl]-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylic acid
CAS Number1429063-06-8
PubChem CID172638405
IUPAC Name(15S,16R,18R)-5-[7-[(15R,17R,18S)-17-carboxy-17-hydroxy-18-methyl-5-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaen-3-yl]heptyl]-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylic acid
Molecular FormulaC59H50N6O10
Molecular Weight1003.1
XLogP7.8
Topological Polar Surface Area211
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count10
Rotatable Bond Count10
Heavy Atom Count75
Formal Charge0
Complexity2260
SMILES
C[C@@]12[C@](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(NC6=O)CCCCCCCC9C1=C2C3=CC=CC=C3N3C2=C2C(=C1C(=O)N9)C1=CC=CC=C1N2[C@H]1C[C@@]([C@@]3(O1)C)(C(=O)O)O)(C(=O)O)O
InChI
InChI=1S/C59H50N6O10/c1-56-58(72,54(68)69)26-38(74-56)62-34-22-12-8-16-28(34)42-46-44(40-30-18-10-14-24-36(30)64(56)50(40)48(42)62)32(60-52(46)66)20-6-4-3-5-7-21-33-45-41-31-19-11-15-25-37(31)65-51(41)49-43(47(45)53(67)61-33)29-17-9-13-23-35(29)63(49)39-27-59(73,55(70)71)57(65,2)75-39/h8-19,22-25,32-33,38-39,72-73H,3-7,20-21,26-27H2,1-2H3,(H,60,66)(H,61,67)(H,68,69)(H,70,71)/t32?,33?,38-,39-,56+,57+,58+,59+/m1/s1
InChIKey
ULKPNQDYRZUKRH-BGHIUSCOSA-N
Chemical Structure
2D Structure
2D structure of (15S,16R,18R)-5-[7-[(15R,17R,18S)-17-carboxy-17-hydroxy-18-methyl-5-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaen-3-yl]heptyl]-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylic acid
CAS: 1429063-06-8
CID: 172638405
Formula: C59H50N6O10
MW: 1003.1
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1003.1
XLogP37.8
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count10
Rotatable Bond Count10
Exact Mass1002.35884181
Monoisotopic Mass1002.35884181
Topological Polar Surface Area211 Ų
Heavy Atom Count75
Formal Charge0
Complexity2260
Isotope Atom Count0
Defined Atom Stereocenter Count6
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19221258-01KT-474
GTR19203700-01KT-5823
GTR19233855-01KT-333
GTR18047537-01IRS-1 (D606) polyclonal antibody
GTR19194097-01KT 1
GTR19203701-01KT-5720
GTR19250347-01KT-253
GTR19236630KT-333
GTR19231426-01KT-531
GTR19197338-01KT-362 fumarate

Alternative Products

CatalogName
T200088-01KT D606
E43S9113IRS-1 (D606) polyclonal antibody

Popular Products