KT-333

CAT: 0013-GTR19236630Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19236630Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

KT-333 is a first-in-class molecular glue that induces selective degradation of STAT3 via the ubiquitin-proteasome system by simultaneously engaging STAT3 and the VHL E3 ligase. This novel mechanism enables potent STAT3 depletion with minimal off-target effects, demonstrating strong anti-tumor activity in hematologic malignancies.

CAS Number

2502186-79-8

Purity

>98%

Smiles

ClC1C (=CC=CC=1OC[C@H] (CCC (N) =O) NC ([C@@H]1CC[C@@H]2CCN (C (C) =O) C[C@@H] (C (N21) =O) NC (C1=CC2C=C (C (=O) P (=O) (O) O) C=CC=2N1) =O) =O) CCCC (N[C@H] (C (N1C[C@@H] (C[C@H]1C (N[C@@H] (C) C1C=CC (C2=C (C) N=CS2) =CC=1) =O) O) =O) C (C) (C) C) =O

Molecular Formula

C60H74CLN10O14PS

Molecular Weight

1257.77993345261

Notes

For research use only.

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GTR19239274-01	KT D606
GTR19231426-01	KT-531
GTR19210617-01	DNK 333
GTR19236277-01	ITI-333
GTR19163277-01	AMG-333

Alternative Products

Catalog	Name
HY-156730-01	KT-333
HY-156730B	KT-333 (diammonium)
T88365-01	KT-333 diammonium
T86788-01	KT-333 ammonium
HY-156730A	KT-333 (ammonium)
B6673-.025	KT 5823
T200088-01	KT D606
453071-01	KT 5720
6738/10	KT 182
MBS515006-01	KT-5823

KT-333

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