KT D606

• Target :

  PAK

• Related Pathways :

  Cytoskeletal Signaling

• Bioactivity :

  KT D606 is a PAK kinase family inhibitor with an IC50 of 4 ?M. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.

• Smiles :

  C[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)C(CCCCCCCC8C=9C%10=C%11C%12=C(C9C(=O)N8)C=%13C(N%12[C@@]%14(O[C@](C)(N%11C=%15C%10=CC=CC%15)[C@](C(O)=O)(O)C%14)[H])=CC=CC%13)NC6=O)C=%16C(N5[C@](O1)(C[C@@]2(C(O)=O)O)[H])=CC=CC%16

• Molecular Formula :

  C59H50N6O10

• Molecular Weight :

  1003.06

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1429063-06-8