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KT-333 diammonium

CAT: 0013-GTR19233848-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19233848-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KT-333 diammonium is a molecular glue degrader that selectively targets STAT3 for ubiquitin-proteasome degradation via VHL recruitment. It demonstrates potent antitumor activity in research models of hematologic malignancies such as T-cell lymphomas and leukemias, supporting its use in both in vitro and in vivo experimental studies.
CAS Number
2502186-80-1
Field of Research
Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
ClC (C (CCCC (N[C@@H] (C (C) (C) C) C (N1[C@@H] (C[C@H] (C1) O) C (N[C@H] (C2=CC=C (C3=C (N=CS3) C) C=C2) C) =O) =O) =O) =CC=C4) =C4OC[C@H] (CCC (N) =O) NC ([C@H]5N6[C@] (CCN (C[C@@H] (C6=O) NC (C7=CC8=CC (C (P ([O-]) ([O-]) =O) =O) =CC=C8N7) =O) C (C) =O) ([H]) CC5) =O.[NH4+].[NH4+]
Molecular Formula
C60H80ClN12O14PS
Molecular Weight
1291.84
Storage Conditions
-20°C
Notes
For research use only.

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