KT-5823

CAT: 0013-GTR19203700-01Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0013-GTR19203700-01Size:100 µg

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Description

KT5823

CAS Number

126643-37-6

Field of Research

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Signal Transduction

Purity

>98%

Bioactivity

PKG inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) or in DMF (up to 20 mg/ml) .

Smiles

C[C@]12N3C=4C5=C (C6=C (C4C=7C3=CC=CC7) CN (C) C6=O) C=8C (N5[C@] (O1) (C[C@@]2 (C (OC) =O) OC) [H]) =CC=CC8

Molecular Formula

C29H25N3O5

Molecular Weight

495.5

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Methyl (9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylate

KT 5823 is an organic heterooctacyclic compound that is 1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to positions 2 and 5 of methyl (3R)-3-methoxy-2-methyltetrahydrofuran-3-carboxylate (the 2S,3R,5R product), and in which the 3 and 3' positions of the biindole moiety have also undergone formal oxidative coupling to positions 3 and 4 of 1-methyl-1,5-dihydro-2H-pyrrol-2-one. It has a role as an EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor. It is a methyl ester, an organic heterooctacyclic compound, an indolocarbazole, a hemiaminal and a gamma-lactam.

CAS Number	126643-37-6
PubChem CID	108152
IUPAC Name	methyl (15S,16R,18R)-16-methoxy-4,15-dimethyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate
Molecular Formula	C29H25N3O5
Molecular Weight	495.5
XLogP	3.5
Topological Polar Surface Area	74.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Heavy Atom Count	37
Formal Charge	0
Complexity	1020

SMILES

C[C@@]12[C@](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CN(C6=O)C)(C(=O)OC)OC

InChI

InChI=1S/C29H25N3O5/c1-28-29(36-4,27(34)35-3)13-20(37-28)31-18-11-7-5-9-15(18)22-23-17(14-30(2)26(23)33)21-16-10-6-8-12-19(16)32(28)25(21)24(22)31/h5-12,20H,13-14H2,1-4H3/t20-,28+,29+/m1/s1

InChIKey

QTYMDECKVKSGSM-YMUMJAELSA-N

Chemical Structure

2D Structure

CAS: 126643-37-6

CID: 108152

Formula: C29H25N3O5

MW: 495.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	495.5
XLogP3	3.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	495.17942091
Monoisotopic Mass	495.17942091
Topological Polar Surface Area	74.9 Å²
Heavy Atom Count	37
Formal Charge	0
Complexity	1020
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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GTR19203701-01	KT-5720
GTR19250347-01	KT-253
GTR19239274-01	KT D606
GTR19236630	KT-333
GTR19231426-01	KT-531
GTR19197338-01	KT-362 fumarate

Alternative Products

Catalog	Name
B6673-.1	KT 5823
MBS515006-01	KT-5823
TBI2083-100UG	KT-5823, PKG inhibitor
A16021-0.1	KT 5823 0.1mg
T32022-01	GW-5823
T200088-01	KT D606
453071-01	KT 5720
6738/10	KT 182
MBS3600323	KT-5720
BUP21029-01	KT-474

KT-5823

Chemical Information

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