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PROTAC SMARCA2 degrader-19

CAT: 0013-GTR19239926-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239926-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC SMARCA2 degrader-19 (Compound 46) is a potent, cell-permeable degrader of SMARCA2, achieving degradation with a DC50 1000 nM in MV4;11) . This tool compound enables targeted protein degradation studies in oncology and epigenetic research, supporting both in vitro and in vivo mechanistic investigations.
CAS Number
2567913-00-0
Field of Research
Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery
Smiles
OC1=C (C=2C=C3C (=CNC3=NN2) C4CCN (CC4) C=5N=CC (=CN5) [C@@H]6CC[C@@H] (C (N[C@H] (C (=O) N7[C@H] (C (NCC8=CC=C (C=C8) C=9SC=NC9C) =O) C[C@@H] (O) C7) [C@] (C) (C) C) =O) CC6) C=CC=C1
Molecular Formula
C50H58N10O5S
Molecular Weight
911.13
Storage Conditions
-20°C
Notes
For research use only.

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