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PROTAC SMARCA2 degrader-26

CAT: 0013-GTR19239641-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239641-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC SMARCA2 degrader-26 (compound 45) is a bifunctional molecule that effectively degrades SMARCA2 (94%) and SMARCA4 (57%) in VCaP cells, demonstrating antiproliferative activity. This tool compound is valuable for in vitro studies in oncology research, particularly for investigating SWI/SNF chromatin remodeling complex function and targeted protein degradation.
CAS Number
2760247-27-4
Field of Research
Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery
Smiles
C ([C@@H] (NC (CN1CCC (NC2=CC=C (C=C2) C=3C=C (N=NC3) C4=C (O) C=CC=C4) CC1) =O) [C@@] (C) (C) C) (=O) N5[C@H] (C (N[C@@H] (C) C6=CC=C (C=C6) C7=C (C) N=CS7) =O) C[C@@H] (O) C5
Molecular Formula
C46H54N8O5S
Molecular Weight
831.04
Storage Conditions
-20°C
Notes
For research use only.

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