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PROTAC SMARCA2/4-degrader-26

CAT: 0931-T89971-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89971-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PROTACs, Epigenetic Reader Domain
Related Pathways
PROTAC, Chromatin/Epigenetic
Bioactivity
PROTAC SMARCA2/4-degrader-26 is a PROTAC targeting the SMARCA2/4 proteins. It is composed of the ligand for PROTAC targeting proteins, 2- (4- (3-Amino-6- (2-hydroxyphenyl) pyridazin-4-yl) piperazin-1-yl) acetic acid, an E3 ligase component (2S,4R) -4-Hydroxy-N- (4- (4-methylthiazol-5-yl) benzyl) pyrrolidine-2-carboxamide, and a PROTAC linker (S) -2-Amino-3,3-dimethylbutanoic acid. The coupled complex of the E3 ubiquitin ligase ligand + Linker is referred to as (S, R, S) -AHPC.
Molecular Formula
C38H47N9O5S
Molecular Weight
741.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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