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PROTAC BTK Degrader-5

CAT: 0013-GTR19230563-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230563-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC BTK Degrader-5 (Compound 3e) is a potent and selective degrader of Bruton's tyrosine kinase (BTK) with a DC50 of 7.0 nM in JeKo-1 cells. It demonstrates antiproliferative activity in lymphoma cell lines and shows potential for research in B-cell malignancies, including chronic lymphocytic leukemia (CLL) .
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C52H57ClFN9O6
Molecular Weight
958.52
Storage Conditions
-20°C
Notes
For research use only.

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