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PROTAC BTK Degrader-13

CAT: 0013-GTR19249601-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249601-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC BTK Degrader-13 is a bifunctional degrader that potently depletes BTK (DC50=0.27 μM) and inhibits its kinase activity (IC50=0.44 μM) . It also suppresses ITK and p38 MAPK, blocking BCR signaling, making it a useful chemical probe for studying B-cell malignancies and autoimmune disorders in vitro.
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C33H30N6O7
Molecular Weight
622.63
Storage Conditions
-20°C
Notes
For research use only.

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