Products for Research Use Only

PROTAC BTK Degrader-9

CAT: 0013-GTR19262052-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262052-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACBTK Degrader-9 (compound 23) is a potent PROTACs degrader that specifically targets BTK. It effectively downregulates the RANKL-activated BTK-PLCγ2-Ca2+-NFATc1 signaling pathway. Consequently, PROTACBTK Degrader-9 inhibits osteoclastogenesis and reduces alveolar bone resorption in a mouse model of periodontitis.
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C46H52FN13O5
Storage Conditions
-20°C
Notes
For research use only.