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PROTAC BTK Degrader-5

CAT: 0931-T79292-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79292-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
PROTACs, BTK
Related Pathways
PROTAC, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
PROTAC BTK Degraders-5 (Compound 3e) is a selective Bruton's tyrosine kinase (BTK) degrader with a DC50 of 7.0 nM in JeKo-1 cells, demonstrating specificity by not affecting CRBN neosubstrates. It also exhibits antiproliferative effects on various lymphoma cell lines, underscoring its potential application in chronic lymphoid malignancies research.
Molecular Formula
C52H57ClFN9O6
Molecular Weight
958.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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