GDC-0310
CAT:
804-HY-139081-04
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GDC-0310
- CAS Number: 1788063-52-4
- UNSPSC Description: GDC-0310 is a selective acyl-sulfonamide Nav1.7 inhibitor, with an IC50 of 0.6 nM for hNav1.7[1].
- Target Antigen: Sodium Channel
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/gdc-0310.html
- Smiles: O=C(NS(=O)(C)=O)C1=CC(C2CC2)=C(OCC3CCN([C@H](C4=CC(Cl)=CC(Cl)=C4)C)CC3)C=C1F
- Molecular Weight: 543.48
- References & Citations: [1]Brian S Safina, et al. Discovery of Acyl-sulfonamide Na v 1.7 Inhibitors GDC-0276 and GDC-0310. J Med Chem. 2021 Mar 25;64(6):2953-2966.|[2]Lei Xu, et al. Voltage-gated sodium channels: structures, functions, and molecular modeling. Drug Discov Today. 2019 Jul;24(7):1389-1397.
- Shipping Conditions: Room Temperature