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PROTAC TTK degrader-2

CAT: 0013-GTR19218644-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218644-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC TTK Degrader-2 is a potent, cell-permeable degrader of threonine tyrosine kinase (TTK/Mps1), demonstrating DC50 values of 3.1 nM (COLO-205) and 12.4 nM (HCT-116) . It effectively reduces TTK protein levels and exhibits robust antitumor efficacy in a COLO-205 xenograft model, supporting its use in targeted protein degradation and oncology research.
CAS Number
2953426-48-5
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C1N (C=2C (=CN=C (NC3=C (OC) C=C (C=C3) N4CCN (C (CCCCCC#CC=5C=C6C (=CC5) CN (C6=O) C7C (=O) NC (=O) CC7) =O) CC4) N2) C (C) =C1) [C@H]8CC[C@@H] (NC (CC) =O) CC8
Molecular Formula
C49H57N9O7
Molecular Weight
884.03
Storage Conditions
-20°C
Notes
For research use only.

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