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PROTAC ALK degrader-2

CAT: 0931-T210290-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210290-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
PROTACs, ALK
Related Pathways
PROTAC, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
PROTACALK degrader-2 (B1-PEG) is a PROTAC-based ALK degrader with a DC50 of 45 nM in H3122 EML4-ALK DC50 (GSH+) . Through PEGylation, PROTACALK degrader-2 can self-assemble into micelles in water, releasing its active form in tumor-specific high-GSH environments.
Molecular Formula
C55H70ClN11O12S3. (C2H4O) n
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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