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PROTAC erf3a Degrader-2

CAT: 0804-HY-163938ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163938ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC erf3a Degrader-2 (Compound C59) is an orally active PROTAC erf3a Degrader. PROTAC erf3a Degrader-2 inhibits protein expression of SRD5A3 and GSPT1 (eRF3a). PROTAC erf3a Degrader-2 inhibits cancer cell proliferation (eg: 22Rv1). PROTAC erf3a Degrader-2 can be used for research of prostate cancer, ovarian cancer, liver cancer, cervical cancer, leukemia, breast cancer. (Red: erf3a ligand ; Black: linker (HY-163960) ; Blue: E3 ligase ligand (HY-W763812) ).
CAS Number
3033871-15-4
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-erf3a-degrader-2.html
Smiles
O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(N[C@H](CCC4)C[C@@H]4NC5=CC(NC([C@H]6CC[C@]([C@@]7([H])[C@@](CC8)([H])[C@@]9([C@@](NC(C=C9)=O)([H])CC7)C)([H])[C@]86C)=O)=CC=C5)=C3C1=O
Molecular Formula
C44H52N6O6
Molecular Weight
760.92
References & Citations
[1]Guangliang Yu, et al. Medicine for treating human tumor by eRF3a targeting protein degradation mechanism. Patent. CN117801051A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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