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PROTAC ALK degrader-2

CAT: 0013-GTR19262852-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262852-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACALK degrader-2 (B1-PEG) is a PROTAC-based ALK degrader with a DC50 of 45 nM in H3122 EML4-ALK DC50 (GSH+) . Through PEGylation, PROTACALK degrader-2 can self-assemble into micelles in water, releasing its active form in tumor-specific high-GSH environments.
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C55H70ClN11O12S3. (C2H4O) n
Storage Conditions
-20°C
Notes
For research use only.

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