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PROTAC TTK degrader-1

CAT: 0013-GTR19218643-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218643-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC TTK degrader-1 is a potent and selective degrader of threonine tyrosine kinase (TTK), demonstrating low-nanomolar DC50 values in colorectal cancer cell lines such as COLO-205 and HCT-116. It has also shown promising in vivo anticancer efficacy in a COLO-205 xenograft mouse model, supporting its use in oncology research for studying TTK biology and targeted protein degradation.
CAS Number
2953426-43-0
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C1N (C=2C (=CN=C (NC3=C (OC) C=C (C=C3) N4CCN (C (CCCC#CC=5C=C6C (=CC5) C (=O) N (C6) C7C (=O) NC (=O) CC7) =O) CC4) N2) C (C) =C1) [C@H]8CC[C@@H] (NC (CC) =O) CC8
Molecular Formula
C47H53N9O7
Molecular Weight
855.98
Storage Conditions
-20°C
Notes
For research use only.

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