Products for Research Use Only
RegisterLogin

PROTAC TEAD degrader-2

CAT: 0013-GTR19277031-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19277031-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PROTACTEAD degrader-2 (Compound 31) is a potent TEAD1 PROTAC degrader with a DC50 of 0.6 nM. It inhibits the YAP/TAZ-TEAD interaction with an IC50 of 1.8 nM and shows significant selective inhibitory activity against YAP-dependent cancer cells, effectively suppressing YAP-mediated transcriptional activity. This compound is applicable in mesothelioma and glioma research.
CAS Number
2918762-17-9
Smiles
O=C (N) C1=CC=C (OC) C (F) =C1C=2C (Cl) =C (F) C=C3OC (C=4C=CC=CC4) (CNC5CCC (C (=O) NCCCCCC=6C=CC=C7C (=O) N (CC76) C8C (=O) NC (=O) CC8) CC5) C (C32) C
Molecular Formula
C49H52ClF2N5O7
Molecular Weight
896.43
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19262478-01PROTAC TEAD degrader-1
GTR19249811-01PROTAC HDAC6 degrader 2
GTR19231490-01PROTAC TG2 degrader-2
GTR19277043-01PROTAC HMGCR Degrader-2
GTR19275904-01PROTAC USP7 Degrader-2
GTR19263524-01PROTAC HDAC degrader-2
GTR19262852-01PROTAC ALK degrader-2
GTR19261719-01PROTAC GPX4 degrader-2
GTR19261256-01PROTAC eDHFR Degrader-2
GTR19218642-01PROTAC SMARCA2 degrader-2

Alternative Products

CatalogName
T209844-01PROTAC TEAD degrader-1
HY-178803PROTAC BCL6 Degrader-2
HY-169072PROTAC MLKL Degrader-2
HY-163938APROTAC erf3a Degrader-2
HY-158036PROTAC STING Degrader-2
HY-128841-01PROTAC MDM2 Degrader-2
T211019-01PROTAC HDAC degrader-2
T210290-01PROTAC ALK degrader-2
T89589-01PROTAC PARP1 degrader-2
HY-111866-01PROTAC RIPK degrader-2

Popular Products