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11β-HSD2-IN-2

CAT: 0804-HY-160618-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-160618-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
11β-HSD2-IN-2 (compound 3) is a selective inhibitor for 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) with an IC50 of 300 nM[1].
CAS Number
1834601-37-4
UNSPSC
12352005
Target
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/11β-hsd2-in-2.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC(N(C(C2=CC=C(OC3=CC=CC(C)=C3)C=C2)=O)C)=CC=C1
Molecular Formula
C22H21NO2
Molecular Weight
331.41
References & Citations
[1]Gargano EM, et al., Addressing cytotoxicity of 1,4-biphenyl amide derivatives: Discovery of new potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors. Bioorg Med Chem Lett. 2016 Jan 1;26 (1) :21-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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