11β-HSD2-IN-2

11β-HSD2-IN-2

• CAS Number: 1834601-37-4
• UNSPSC Description: 11β-HSD2-IN-2 (compound 3) is a selective inhibitor for 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) with an IC50 of 300 nM[1].
• Target Antigen: 11β-HSD
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/11β-hsd2-in-2.html
• Purity: 99.96
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC1=CC(N(C(C2=CC=C(OC3=CC=CC(C)=C3)C=C2)=O)C)=CC=C1
• Molecular Weight: 331.41
• References & Citations: [1]Gargano EM, et al., Addressing cytotoxicity of 1,4-biphenyl amide derivatives: Discovery of new potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors. Bioorg Med Chem Lett. 2016 Jan 1;26(1):21-4.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported