11β-HSD1-IN-14
CAT:
804-HY-162026
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
11β-HSD1-IN-14
- CAS Number: 946394-50-9
- UNSPSC Description: 11β-HSD1-IN-14 (Compound 17) is a selective inhibitor for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1), with IC50 of 74 nM for human HSD1, and 603 nM for HSD1 expressed HEK293 cell[1].
- Target Antigen: 11β-HSD
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/11β-hsd1-in-14.html
- Solubility: 10 mM in DMSO
- Smiles: O=S(C1=CC=C(C2=CC=CC=C2)C=C1)(N3CCN(CC3)C4=NC=CC=C4C(F)(F)F)=O
- Molecular Weight: 447.47
- References & Citations: [1]Sun D, et al., Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1). Bioorg Med Chem Lett. 2008 Jun 15;18(12):3513-6.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported