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11β-HSD1-IN-1

CAT: 0804-HY-U00325-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-U00325-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1), with an IC50 of 52 nM, and used for the treatment of pain.
CAS Number
1203956-47-1
UNSPSC
12352005
Target
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4H-1,2,4-Triazole,_3-_2-chloro-4-fluorophenyl_-4-methyl-5-[1-methyl-1-_2,4,6-trifluorophenoxy_ethyl]-.html
Purity
99.80
Solubility
10 mM in DMSO
Smiles
CC(C1=NN=C(C2=CC=C(F)C=C2Cl)N1C)(C)OC3=C(F)C=C(F)C=C3F
Molecular Formula
C18H14ClF4N3O
Molecular Weight
399.77
References & Citations
[1]THERAPEUTIC AGENT FOR PAIN. WO2012033070A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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