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11β-HSD1-IN-11

CAT: 0804-HY-151627Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-151627Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
11β-HSD1-IN-11 (Compound c1a) is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively[1].
CAS Number
859721-81-6
UNSPSC
12352005
Target
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/11β-hsd1-in-11.html
Solubility
10 mM in DMSO
Smiles
FC(C1=CC=C(C(CS(=O)(C2=CC=CC=C2)=O)=O)C=C1)(F)F
Molecular Formula
C15H11F3O3S
Molecular Weight
328.31
References & Citations
[1]Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12 (1) :16268.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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