Products for Research Use Only
RegisterLogin

11β-HSD2-IN-1

CAT: 0804-HY-157161Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-157161Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
11β-HSD2-IN-1 (compound CDSN) is a potent inhibitor of 11β-HSD2, inhibiting the metabolism of Cholestane-3β,5α,6β-triol (CT) in cells by 11β-HSD2 into the tumor promoter, carcinosterone. 11β-HSD2-IN-1 inhibits testosterone biosynthesis, thereby inhibiting MCF-7 cell proliferation. 11β-HSD2-IN-1 has immune activity and antiviral infection effects[1].
UNSPSC
12352100
Target
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/11β-hsd2-in-1.html
Solubility
10 mM in DMSO
Smiles
CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])C[C@@H](O)[C@@]4(O)C[C@@H](S(=O)(O)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Molecular Formula
C27H48O5S
Molecular Weight
484.73
References & Citations
[1]de Médina P et al. Chemical synthesis and biochemical properties of cholestane-5α,6β-diol-3-sulfonate: A non-hydrolysable analogue of cholestane-5α,6β-diol-3β-sulfate. J Steroid Biochem Mol Biol. 2023 Nov;234:106396.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-160618-0111β-HSD2-IN-2
HY-U00325-0111β-HSD1-IN-1
HY-15162711β-HSD1-IN-11
HY-179602PROTAC 11β-HSD1 Degrader 1
HY-162026-0111β-HSD1-IN-14
HY-W32424311β-HSD1-IN-9
HY-167696-0111β-HSD1-IN-16
HY-W32422011β-HSD1-IN-10
HY-W129359-0111β-HSD1-IN-8
HY-14156-0111β-HSD1-IN-15

Alternative Products

CatalogName
T208325-0111β-HSD2-IN-1
T85382-0111β-HSD2-IN-2
BUP21466-0111ß-HSD2-IN-2
sc-4137911β-HSD2 siRNA (h)
sc-27059811β-HSD2 siRNA (r)
sc-36552911β-HSD2 (C-9)
sc-270598-PR11β-HSD2 (r) -PR
sc-4138011β-HSD2 siRNA (m)
sc-41380-PR11β-HSD2 (m) -PR
sc-41379-PR11β-HSD2 (h) -PR

Popular Products