PROTAC SMARCA2 degrader-29

• UNSPSC Description:

  PROTAC SMARCA2 degrader-29 (Example 87) is a PROTAC SMARCA2 (BRM) degrader, with DC50 of 10-100 nM (BRM) and > 1 μM (BRG1, also known as SMARCA2) respectively[1].

• Target Antigen:

  Epigenetic Reader Domain; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-smarca2-degrader-29.html

• Smiles:

  CC(C)[C@@H](C(N1C[C@H](O)C[C@H]1C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)C4=CC(N5CCC(N6CCC(C7=CC8=C(C=C(C9=CC=CC=C9O)N=N8)S7)CC6)CC5)=NO4

• Molecular Weight:

  875.11

• References & Citations:

  [1]Matthew Netherton, et al. Compounds and uses thereof. Patent. WO2022240825

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2865193-25-3