PROTAC SMARCA2 degrader-24

• CAS Number: 2755761-70-5
• UNSPSC Description: PROTAC SMARCA2 degrader-24 (Compound 34) is a PROTAC degrader for SMARCA2 with a DC50 SMARCA4 with a DC50 > 10 μM in HeLa[1].
• Target Antigen: Epigenetic Reader Domain; PROTACs
• Type: Reference compound
• Related Pathways: Epigenetics;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-smarca2-degrader-24.html
• Smiles: CC1=C(SC=N1)C2=CC=C(C=C2)[C@@H](NC([C@@H]3C[C@H](CN3C(C(C(C)C)C4=CC(CCN(CCN5CCN6C7=C(NC[C@H]6C5)N=NC(C8=C(C=CC=C8)O)=C7)C)=NO4)=O)O)=O)C
• Molecular Weight: 849.06
• References & Citations: [1]Combs AP, et al., Brm targeting compounds and associated methods of use. WO2021252666.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported