MRE 0094

• Description:

  MRE 0094 (Sonedenoson) is a selective activator for adenosine receptor A2A, with a Ki of 490 nM. MRE 0094 exhibits anti-platelet and anti-inflammatory activities[1].

• Product Name Alternative:

  Sonedenoson

• UNSPSC:

  12352005

• Target:

  Adenosine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/mre-0094.html

• Purity:

  99.79

• Smiles:

  NC1=NC(OCCC2=CC=C(Cl)C=C2)=NC3=C1N=CN3[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O

• Molecular Formula:

  C18H20ClN5O5

• Molecular Weight:

  421.83

• References & Citations:

  [1]Boncler M, et al., Adenosine receptor agonists deepen the inhibition of platelet aggregation by P2Y12 antagonists. Vascul Pharmacol. 2019 Feb;113:47-56.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  Adenosine A2A receptor (A2AR) ; Adenosine A2B receptor (A2BR)

• CAS Number:

  [131865-88-8]