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F0840-0093

CAT: 0804-HY-178463Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178463Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
F0840-0093 is a highly selective estrogen receptor α (ERα) degrader. F0840-0093 exhibits potent antiproliferative activity against T47D cells with an IC50 value of 4.65 μM. F0840-0093 is promising for research of estrogen receptor-positive (ER+) breast cancer[1].
CAS Number
503429-76-3
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
O=C1C2=CC=CC3=C2C(C(N1CCN4CCN(CC4)C[C@@H](COCC5=CC=C(C=C5)Cl)O)=O)=CC=C3
Molecular Formula
C28H30ClN3O4
Molecular Weight
508.01
References & Citations
[1]Chen M, et al. Identification of novel selective estrogen receptor degraders (SERD) via physics-based and deep-learning-based virtual screening and Bioassys. Bioorg Chem. 2025 Oct;165:109011.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERα

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