MRE-269 (Standard)

• Description:

  MRE-269 (Standard) is the analytical standard of MRE-269. This product is intended for research and analytical applications. MRE-269 is an active metabolite of selexipag, and acts as a selective IP receptor agonist.

• UNSPSC:

  12352100

• Target:

  Prostaglandin Receptor; Reference Standards

• Related Pathways:

  GPCR/G Protein; Others

• Field of Research:

  Cardiovascular Disease; Endocrinology

• Smiles:

  OC(COCCCCN(C(C)C)C1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)N=C1)=O

• Molecular Formula:

  C25H29N3O3

• Molecular Weight:

  419.52

• References & Citations:

  [1]Fuchikami C, et al. A comparison of vasodilation mode among selexipag (NS-304; [2-{4-[ (5,6-diphenylpyrazin-2-yl) (isopropyl) amino]butoxy}-N- (methylsulfonyl) acetamide]), its active metabolite MRE-269 and various prostacyclin receptor agonists in rat, porcin|[2]Orie NN, et al. Differential actions of the prostacyclin analogues treprostinil and iloprost and the selexipag metabolite, MRE-269 (ACT-333679) in rat small pulmonary arteries and veins. Prostaglandins Other Lipid Mediat. 2013 Oct;106:1-7|[3]Kuwano K, et al. A long-acting and highly selective prostacyclin receptor agonist prodrug, 2-{4-[ (5,6-diphenylpyrazin-2-yl) (isopropyl) amino]butoxy}-N- (methylsulfonyl) acetamide (NS-304), ameliorates rat pulmonary hypertension with unique relaxant responses

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [475085-57-5]