JJC12-009

• Description:

  JJC12-009 is a dopamine transporter (DAT) inhibitor, with a Ki of 5.45 nM[1].

• UNSPSC:

  12352005

• Target:

  Dopamine Transporter

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/jjc12-009.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(CC1=CC=CC=C1)CN2CCN(CCS(CC3=CC=CC=C3C4=CC=C(Cl)C=C4)=O)CCC2

• Molecular Formula:

  C29H35ClN2O2S

• Molecular Weight:

  511.12

• References & Citations:

  [1]Ku T C, et al. Series of (([1, 1′-Biphenyl]-2-yl) methyl) sulfinylalkyl Alicyclic Amines as Novel and High Affinity Atypical Dopamine Transporter Inhibitors with Reduced hERG Activity[J]. ACS Pharmacology & Translational Science, 2024.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported