LMD-009

CAT: 0804-HY-121885-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-121885-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM[1].
CAS Number
[950195-51-4]
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/lmd-009.html
Concentration
10mM
Purity
99.35
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C1NCN(CCC2=CC=CC=C2)C13CCN(CC4=CC=CC(OC5=CC=CC=C5OC)=C4)CC3
Molecular Formula
C29H33N3O3
Molecular Weight
471.59
References & Citations
[1]Jensen PC, et al. Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8. Mol Pharmacol. 2007 Aug;72 (2) :327-40.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR8

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