Antitumor agent-37

• Target:

  Others|||Apoptosis

• Related Pathways:

  Apoptosis|||Others

• Bioactivity:

  Antitumor agent-37 exhibits potent anti-proliferative and anti-metastatic effects. antitumor agent-37 induces severe DNA damage, leading to high expression of ?-H2AX and p53. antitumor agent-37 induces apoptosis by exploiting the mitochondrial apoptosis pathway Bcl-2/Bax/caspase3. Antitumor agent-37 inhibits PD-L1 expression, increases CD3+ and CD8+ T-infiltrating cells in tumour tissue and significantly improves the immune response.

• Molecular Formula:

  C16H18Cl2N2O4Pt

• Molecular Weight:

  568.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  9007-83-4