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Antitumor agent-37

CAT: 0931-T64022-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64022-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Target
Others, Apoptosis
Related Pathways
Apoptosis, Others
Bioactivity
Antitumor agent-37 exhibits potent anti-proliferative and anti-metastatic effects. antitumor agent-37 induces severe DNA damage, leading to high expression of γ-H2AX and p53. antitumor agent-37 induces apoptosis by exploiting the mitochondrial apoptosis pathway Bcl-2/Bax/caspase3. Antitumor agent-37 inhibits PD-L1 expression, increases CD3+ and CD8+ T-infiltrating cells in tumour tissue and significantly improves the immune response.
Molecular Formula
C16H18Cl2N2O4Pt
Molecular Weight
568.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C