Antimalarial agent 10

• Target:

  Others|||Parasite

• Related Pathways:

  Microbiology/Virology|||Others

• Bioactivity:

  Antimalarial agent 10 (Compound 17b) is an amino alcohol-quinoline compound. It exhibits antimalarial activity against Pf3D7 (IC50: 14.9 nM) and PfW2 (IC50: 11 nM) with a selectivity index greater than 770, irrespective of the cell line.

• Smiles:

  C(F)(F)(F)C=1C2=C(C([C@@H](CN[C@@H](CC3=CC=CC=C3)COC)O)=CC(C(F)(F)F)=N2)C=CC1

• Molecular Formula:

  C23H22F6N2O2

• Molecular Weight:

  472.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2747280-03-9